Early Postoperative Dupilumab After Revision Endoscopic Sinus Surgery for CRSwNP: A Real-World Single-Centre Study

Early postoperative initiation of dupilumab after revision ESS was associated with improvements in endoscopic findings, symptom severity, and quality of life. These findings suggest that the early postoperative period may represent a therapeutic window in selected patients with severe recurrent CRSwNP. However, results should be interpreted with caution and considered hypothesis-generating.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-15
DOI
https://doi.org/10.3390/jcm15083015
Primary Topic
Sinusitis and nasal conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Early Postoperative Dupilumab After Revision Endoscopic Sinus Surgery for CRSwNP: A Real-World Single-Centre Study

Juan David Gutiérrez Posso, Aitor Zabala-Lopez de Maturana
Journal of Clinical Medicine
Sinusitis and nasal conditions
article

Early Postoperative Dupilumab After Revision Endoscopic Sinus Surgery for CRSwNP: A Real-World Single-Centre Study

Juan David Gutiérrez Posso, Aitor Zabala-Lopez de Maturana
article en

Abstract

Early postoperative initiation of dupilumab after revision ESS was associated with improvements in endoscopic findings, symptom severity, and quality of life. These findings suggest that the early postoperative period may represent a therapeutic window in selected patients with severe recurrent CRSwNP. However, results should be interpreted with caution and considered hypothesis-generating.

Journal of Clinical MedicineVol. 15(8)
BioCruces Health research Institute (ES), Hospital de Basurto (ES)
Good health and well-being
Openalex Percentile: Top 19%
Sinusitis and nasal conditions
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