Respiratory ventilation modes in selective ophthalmic arterial chemotherapy for pediatric retinoblastoma under general anesthesia

Objective: To determine the optimal ventilation strategy for pediatric patients with retinoblastoma undergoing selective ophthalmic arterial chemotherapy (SOAC) by comparing the intraoperative effects of volume-controlled (VCV), pressure-controlled (PCV), and pressure-controlled volume-guaranteed (PCV-VG) ventilation. Methods: ), arterial blood gases, and clinical complications were recorded and analyzed. Results: < 0.05. No significant differences of other indicators were found among the three groups. Conclusion: Altogether, compared with the VCV, both PCV and PCV-VG modes produced beneficial lower peak airway pressures during SOAC, thus conducing to prevent mechanical ventilation lung injury.