Health-Related Quality of Life in Previous Versus Current Opiate Users Receiving HCV Therapy: Registry-Based Evidence
: Compared with opiate-dependent patients in OAT, POUs showed less psychotropic substance use and better HRQoL. Compared with NOU patients and the general population, mental health problems were especially increased. Challenges persist for POUs even during abstinence from opiates, highlighting the need for targeted interventions tailored to the specific needs of this population.
Authors
- Christiane Sybille Schmidt (ORCID: https://orcid.org/0000-0003-1999-2073)
- Norbert Scherbaum (ORCID: https://orcid.org/0000-0003-1759-6990)
- Uwe Naumann
- H. Klinker
- Renate Heyne
- Michael Specka (ORCID: https://orcid.org/0000-0001-5194-7876)
- Fabrizio Schifano (ORCID: https://orcid.org/0000-0002-4178-5401)
- Peter Buggisch (ORCID: https://orcid.org/0000-0002-3076-3960)
- Jens Reimer (ORCID: https://orcid.org/0009-0007-5406-5319)
- Ralph Link
- Bernd Schulte
- Heiner Wedemeyer
- Stefan Christensen
Institutions
- University of Hertfordshire (GB)
- Universität Hamburg (DE)
- Medizinische Hochschule Hannover (DE)
- University Hospital Münster (DE)
- Klinikum Itzehoe (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Comenius-Institut (DE)
- Essen University Hospital (DE)
- Universitätsklinikum Würzburg (DE)
- Institute for Interdisciplinary Medicine (DE)
- German Liver Foundation (DE)
- University of Duisburg-Essen (DE)
- Offenburg University of Applied Sciences (DE)
- Praxis (EE)
Publication Details
- Journal
- Brain Sciences
- Published
- 2026-04-15
- DOI
- https://doi.org/10.3390/brainsci16040414
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bristol-Myers Squibb
- Gilead Sciences
- Deutsches Zentrum für Infektionsforschung
- Stiftung für Leberkrankheiten
- Universität Duisburg-Essen
- Cilag