Association Between Renal Fat Fraction and Early Biomarkers of Kidney Injury in Patients with Type 2 Diabetes Mellitus

The study systematically demonstrates a significant association between renal FF and early biomarkers of kidney injury in T2DM, which may suggest the potential role of renal fat accumulation in the pathogenesis of diabetic nephropathy. These findings provide clinical data support for the development of a fat-targeted intervention study. Future research should further elucidate the long-term mechanistic role of renal FF in diabetic nephropathy, as well as its potential value in early diagnosis and therapeutic applications.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-15
DOI
https://doi.org/10.3390/jcm15083025
Primary Topic
Cardiovascular Disease and Adiposity
Type
article
Field-Weighted Citation Impact
0.00

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article

Association Between Renal Fat Fraction and Early Biomarkers of Kidney Injury in Patients with Type 2 Diabetes Mellitus

Yangmei Zhou, Yao Qin, Shichun Huang, Y Ying Mao et al.
Journal of Clinical Medicine
Cardiovascular Disease and Adiposity
article

Association Between Renal Fat Fraction and Early Biomarkers of Kidney Injury in Patients with Type 2 Diabetes Mellitus

Yangmei Zhou, Yao Qin, Shichun Huang, Y Ying Mao, Eisha Adnan, Lingjun Sun, Tingting Luo, Zhuo Chen, Lina Mao, Tinghua Zan
article en

Abstract

The study systematically demonstrates a significant association between renal FF and early biomarkers of kidney injury in T2DM, which may suggest the potential role of renal fat accumulation in the pathogenesis of diabetic nephropathy. These findings provide clinical data support for the development of a fat-targeted intervention study. Future research should further elucidate the long-term mechanistic role of renal FF in diabetic nephropathy, as well as its potential value in early diagnosis and therapeutic applications.

Journal of Clinical MedicineVol. 15(8)
The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
National Natural Science Foundation of China, China Postdoctoral Science Foundation, National Science and Technology Major Project
Good health and well-being
Openalex Percentile: Top 23%
Cardiovascular Disease and Adiposity
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