Drug-drug interactions with Mexidol in patients with ischemic stroke: Analysis of data from randomized clinical trials

OBJECTIVE: Identification of drug-drug interaction of Mexidol when used in patients with ischemic stroke. MATERIAL AND METHODS: The data from randomized controlled clinical trials (RCTs) of the efficacy and safety of Mexidol, EPICA and MIR, in patients with ischemic stroke were analyzed. RESULTS: >0.05 in all comparison pairs). CONCLUSION: The analysis did not reveal drug interactions when using Mexidol and all types of concomitant therapy in patients with ischemic stroke. This study confirmed the high safety and good tolerability when using Mexidol in patients receiving multiple medications at the same time.