HDAC3 Regulates Transcriptional Networks Governing Decidualization
mice compared with controls. These findings demonstrate that HDAC3 is a key regulator of the transcriptional and signaling networks required for successful decidualization. Collectively, our study provides a comprehensive transcriptomic profile of HDAC3-deficient uteri and uncovers key molecular mechanisms underlying impaired decidualization, thereby advancing our understanding of uterine function and pregnancy establishment.
Authors
- Loan Thi Kim Nguyen (ORCID: https://orcid.org/0000-0003-3799-0514)
- Shamsun Nahar Begum (ORCID: https://orcid.org/0000-0002-0159-5558)
- Dinh Nam Tran (ORCID: https://orcid.org/0000-0002-8278-1386)
- Jae‐Wook Jeong (ORCID: https://orcid.org/0000-0002-5368-6478)
- Jung‐Yoon Yoo (ORCID: https://orcid.org/0000-0001-9366-3863)
- Tae Hoon Kim (ORCID: https://orcid.org/0000-0001-7823-5457)
Institutions
- Yonsei University (KR)
- University of Missouri Health System (US)
Publication Details
- Journal
- The FASEB Journal
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1096/fj.202600629r
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea
- National Institutes of Health
- National Institute of Child Health and Human Development
- Eunice Kennedy Shriver National Institute of Child Health and Human Development