Intrawound Tobramycin Plus Vancomycin to Prevent Surgical Site Infection in Tibial Fractures

The study compared whether applying tobramycin and vancomycin powders topically to a surgical incision during closure of definitive fixation was more effective than applying vancomycin powder alone in reducing deep surgical site infection in periarticular tibial fractures.

Publication Details

Journal
JAMA
Published
2026-04-15
DOI
https://doi.org/10.1001/jama.2026.4070
Primary Topic
Orthopedic Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Intrawound Tobramycin Plus Vancomycin to Prevent Surgical Site Infection in Tibial Fractures

JAMA
Orthopedic Infections and Treatments
article

Intrawound Tobramycin Plus Vancomycin to Prevent Surgical Site Infection in Tibial Fractures

article en

Abstract

The study compared whether applying tobramycin and vancomycin powders topically to a surgical incision during closure of definitive fixation was more effective than applying vancomycin powder alone in reducing deep surgical site infection in periarticular tibial fractures.

JAMA
Good health and well-being
Openalex Percentile: Top 7%
Orthopedic Infections and Treatments
DOISourceOpenAlex
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Intrawound Tobramycin Plus Vancomycin to Prevent Surgical Site Infection in Tibial Fractures · JAMA (2026) | TGRS Research Map | TGRS