Simplified approaches to kinetic isotope effects in cytochrome P450-catalyzed reactions and relevance to deuterated drugs

. Some applications of KIEs to the design and development of deuterated drugs are presented.

Authors

Institutions

Publication Details

Journal
Drug Metabolism Reviews
Published
2026-04-15
DOI
https://doi.org/10.1080/03602532.2026.2657290
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Simplified approaches to kinetic isotope effects in cytochrome P450-catalyzed reactions and relevance to deuterated drugs

F. Peter Guengerich
Drug Metabolism Reviews
Pharmacogenetics and Drug Metabolism
article

Simplified approaches to kinetic isotope effects in cytochrome P450-catalyzed reactions and relevance to deuterated drugs

F. Peter Guengerich
article en

Abstract

. Some applications of KIEs to the design and development of deuterated drugs are presented.

Drug Metabolism Reviews
Vanderbilt University (US)
National Institutes of Health
Openalex Percentile: Top 17%
Pharmacogenetics and Drug Metabolism
DOISourceOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.