Effect of intravitreal injection of dexamethasone implant on the corneal morphology of young adults with central retinal vein occlusion

AIM: To investigate the effect of intravitreal injection of dexamethasone (DEX) implants on the corneal morphology of young adults with central retinal vein occlusion (CRVO). METHODS: This was a retrospective study. The information of all patients was collected from the hospital information system. Patients diagnosed with CRVO were included. Corneal morphometric analysis was performed 1, 3, 6, and 12mo after the intravitreal injection of DEX. Corneal endothelial cell density (ECD), hexagonal cell ratio (HEX), and coefficient of variation (CV), central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber angle (ACA), and anterior chamber volume (ACV) were evaluated. RESULTS: >0.05). No significant difference was found in corneal morphology between single and repeated DEX implant injections. CONCLUSION: In young adults with CRVO, intravitreal injection of DEX can temporarily decrease ECD. However, the remaining corneal endothelial morphological characteristics and anterior chamber parameters are unaffected.