Clinical Outcomes of Cardiac Implantable Electronic Device Infections in Octogenarians: A 20-Year Retrospective Cohort Study

Octogenarians suffering from CIED infections display highly distinct clinical and microbiological profiles, characterized predominantly by elevated rates of localized pocket infections, specific opportunistic pathogens, and a severe underlying comorbidity burden. Crucially, our findings indicate that with the application of modern extraction and management protocols, advanced age alone does not intrinsically correlate with increased in-hospital mortality. Future prevention and perioperative management strategies tailored to this rapidly expanding demographic must heavily prioritize the mitigation of pocket-related complications, particularly considering the high prevalence of concurrent anticoagulation therapy.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-15
DOI
https://doi.org/10.3390/jcm15082996
Primary Topic
Cardiac pacing and defibrillation studies
Type
article
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article

Clinical Outcomes of Cardiac Implantable Electronic Device Infections in Octogenarians: A 20-Year Retrospective Cohort Study

Gabriele Romano, Migdat Mustafi, Rawa Arif, Patricia Kraft et al.
Journal of Clinical Medicine
Cardiac pacing and defibrillation studies
article

Clinical Outcomes of Cardiac Implantable Electronic Device Infections in Octogenarians: A 20-Year Retrospective Cohort Study

Gabriele Romano, Migdat Mustafi, Rawa Arif, Patricia Kraft, M K Karck, Sameer Al-Maisary, Mario Jesus Guzman-Ruvalcaba
article en

Abstract

Octogenarians suffering from CIED infections display highly distinct clinical and microbiological profiles, characterized predominantly by elevated rates of localized pocket infections, specific opportunistic pathogens, and a severe underlying comorbidity burden. Crucially, our findings indicate that with the application of modern extraction and management protocols, advanced age alone does not intrinsically correlate with increased in-hospital mortality. Future prevention and perioperative management strategies tailored to this rapidly expanding demographic must heavily prioritize the mitigation of pocket-related complications, particularly considering the high prevalence of concurrent anticoagulation therapy.

Journal of Clinical MedicineVol. 15(8)
Heidelberg University (DE), University Hospital Heidelberg (DE), Saarland University (DE)
Good health and well-being
Openalex Percentile: Top 23%
Cardiac pacing and defibrillation studies
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