CDG-MACE score: an interpretable scoring model for risk stratification in emergency chest pain with normal ECG
The CDG-MACE Score combines dynamic ECG modeling with a SHAP-linearized scoring system to achieve discrimination with global interpretability, enabling safe exclusion of low-risk patients without typical ischemic ECG changes. External validation suggests robustness and clinical utility; additional multicenter prospective studies and fairness monitoring are warranted.
Authors
- Chunmiao Liang
- Qinghua Sun (ORCID: https://orcid.org/0000-0003-3908-307X)
- Rugang Liu (ORCID: https://orcid.org/0000-0002-4270-9507)
- Cong Wang (ORCID: https://orcid.org/0000-0002-5601-2145)
- Hao Zhang (ORCID: https://orcid.org/0000-0003-4276-5477)
- Tianyuan Qi
- Jiali Li
- Jiaojiao Pang
- Yuguo Chen
Institutions
- University of Jinan (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Physiological Measurement
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1088/1361-6579/ae601a
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province