Neurological disorders induced by nitrous oxide abuse: analysis of 57 clinical cases

OBJECTIVE: To analyze neurological disorders induced by nitrous oxide use and to evaluate the effectiveness of various pathogenetic therapy regimens. MATERIAL AND METHODS: Clinical and paraclinical data from 57 patients (45 men and 12 women), aged 18 to 55 years (median 26 years [LQ 21; UQ 33]), with a history of nitrous oxide abuse were analyzed. RESULTS: and homocysteine levels, regardless of the route of administration. CONCLUSION: supplementation in patients abusing nitrous oxide has been demonstrated.

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Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2026-04-15
DOI
https://doi.org/10.17116/jnevro202612603125
Primary Topic
Folate and B Vitamins Research
Type
article
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article

Neurological disorders induced by nitrous oxide abuse: analysis of 57 clinical cases

Д. А. Гришина, Н. А. Супонева, N.N. Turovets
S S Korsakov Journal of Neurology and Psychiatry
Folate and B Vitamins Research
article

Neurological disorders induced by nitrous oxide abuse: analysis of 57 clinical cases

Д. А. Гришина, Н. А. Супонева, N.N. Turovets
article en

Abstract

OBJECTIVE: To analyze neurological disorders induced by nitrous oxide use and to evaluate the effectiveness of various pathogenetic therapy regimens. MATERIAL AND METHODS: Clinical and paraclinical data from 57 patients (45 men and 12 women), aged 18 to 55 years (median 26 years [LQ 21; UQ 33]), with a history of nitrous oxide abuse were analyzed. RESULTS: and homocysteine levels, regardless of the route of administration. CONCLUSION: supplementation in patients abusing nitrous oxide has been demonstrated.

S S Korsakov Journal of Neurology and PsychiatryVol. 126(3)
Research Center of Neurology (RU)
Good health and well-being
Openalex Percentile: Top 19%
Folate and B Vitamins Research
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