Thy1 <sup>+</sup> Periosteal Osteoprogenitors Contribute to Mandibular Bone Defect Healing in Mice
OBJECTIVE: To investigate the distribution, lineage fate, and reparative function of Thy1 lineage cells in the mouse mandible. METHODS: periosteal cells within hydrogel scaffolds. RESULTS: periosteal cells enhanced bone formation within the defect. CONCLUSIONS: Thy1 lineage periosteal cells represent a functionally important osteoprogenitor population in mandibular bone regeneration, providing a cellular framework for future mechanistic and translational studies.
Authors
- L J Zhang
- Jiansheng Su (ORCID: https://orcid.org/0009-0000-0199-4543)
- Wenjing Wu
Institutions
- Tongji University (CN)
Publication Details
- Journal
- Oral Diseases
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1111/odi.70309
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China