Value of different nutritional and inflammatory markers for diagnosis of peritonitis in patients undergoing peritoneal dialysis

< 0.01) as an independent risk factor. ROC analysis revealed moderate diagnostic performance for PAR (AUC = 0.700), NLR (AUC = 0.718), MLR (AUC = 0.717), and SIRI (AUC = 0.688), but the neutrophil-to-monocyte ratio (NMR) and lymphocyte-to-monocyte ratio (LMR) performed poorly. A combined PAR/NLR/MLR/SIRI model achieved an AUC of 0.798. These findings link poor nutrition and heightened inflammation to peritonitis in PD patients, suggesting blood-derived indices, such as PAR, NLR, MLR, and SIRI, may serve as adjunctive markers to assist the established diagnostic methods.