Tubular adenoma of the urinary bladder in a female patient: An extremely rare entity clinically mimicking urothelial malignancy

Tubular adenoma of the urinary bladder is an exceptionally rare intestinal-type glandular neoplasm that may mimic urothelial malignancy. Among approximately 82 reported enteric-type bladder adenomas, only four represent pure tubular adenomas. We report a case in a 78-year-old woman presenting with gross hematuria. Cystoscopy revealed a suspicious lesion, and transurethral resection was performed. Histopathologic examination showed tubular glands with intestinal differentiation without villous architecture. Immunohistochemistry supported intestinal differentiation. To our knowledge, this represents the fifth reported case. Recognition of this entity is essential to avoid misdiagnosis and overtreatment.

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Publication Details

Journal
Urology Case Reports
Published
2026-04-15
DOI
https://doi.org/10.1016/j.eucr.2026.103445
Primary Topic
Urinary and Genital Oncology Studies
Type
article
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article

Tubular adenoma of the urinary bladder in a female patient: An extremely rare entity clinically mimicking urothelial malignancy

Asilhan Sabuncu, Esra Paşaoğlu, Cansu Taşpınar, Ezgi Duman Kurt et al.
Urology Case Reports
Urinary and Genital Oncology Studies
article

Tubular adenoma of the urinary bladder in a female patient: An extremely rare entity clinically mimicking urothelial malignancy

Asilhan Sabuncu, Esra Paşaoğlu, Cansu Taşpınar, Ezgi Duman Kurt, Şule Özsoy, İsmail Engin Kandıralı
article en

Abstract

Tubular adenoma of the urinary bladder is an exceptionally rare intestinal-type glandular neoplasm that may mimic urothelial malignancy. Among approximately 82 reported enteric-type bladder adenomas, only four represent pure tubular adenomas. We report a case in a 78-year-old woman presenting with gross hematuria. Cystoscopy revealed a suspicious lesion, and transurethral resection was performed. Histopathologic examination showed tubular glands with intestinal differentiation without villous architecture. Immunohistochemistry supported intestinal differentiation. To our knowledge, this represents the fifth reported case. Recognition of this entity is essential to avoid misdiagnosis and overtreatment.

Urology Case ReportsVol. 66
Bağcılar Eğitim ve Araştırma Hastanesi (TR)
Gender equality
Openalex Percentile: Top 26%
Urinary and Genital Oncology Studies
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