Identification of a prognostic model using immune related genes combined with tumour mutational burden and T cell infiltration in triple‑negative breast cancer

T-cell counts and inversely associated with M0 and M2 macrophage counts. The overall risk score and CXCL13 expressions were all positively correlated with multiple immune checkpoint genes, while TAPBPL expression correlated positively with CTLA4, TIM3 and TIGIT. In summary, the present study provided a TMB- and T-cell infiltration-based IRG signature that is prognostic and may potentially support the prediction of immunotherapy responsiveness in TNBC in the future.