Revealing novel subtypes of synovial sarcoma through single cell transcriptomics
SyS has the highest levels of differentiation and lowest levels of the core oncogenic program. Our data complements the traditional classification of SyS and suggests that the monophasic mesenchymal SyS might consist of two molecular subtypes.
Authors
- Timur I. Fetisov (ORCID: https://orcid.org/0000-0002-5082-9883)
- Maxim E. Menyailo (ORCID: https://orcid.org/0000-0003-4630-4934)
- Marianna G. Yakubovskaya (ORCID: https://orcid.org/0000-0002-9710-8178)
- Artem L. Toropov (ORCID: https://orcid.org/0009-0009-1413-955X)
- Sofya A. Khazanova (ORCID: https://orcid.org/0000-0002-8350-0021)
- Polina Shtompel (ORCID: https://orcid.org/0009-0000-8673-597X)
- Evgeny V. Denisov
- Alexander V. Ikonnikov
- Nikolay A. Kozlov
- Ekaterina A. Trapeznikova
- Anna M. Stroganova
- Anastasia A. Tararykova
- Kirill I. Kirsanov
- Daria A. Meshkova
- Elena E. Kopantseva
Institutions
- Peoples' Friendship University of Russia (RU)
Publication Details
- Journal
- npj Systems Biology and Applications
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1038/s41540-026-00711-5
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00