Cardioprotective effect of hydroalcoholic extract stem bark of <i>Xeroderris stuhlmannii</i> on cadmium chloride-induced hypertension and its possible vasorelaxant mechanism on isolated aortic rats

BACKGROUND: is a medicinal plant, widely used in Cameroonian folk medicine to treat hypertension. OBJECTIVE: in hypertensive rats and to explore the vasorelaxant mechanisms of its hydroalcoholic extract and to determine the compounds responsible of the activities. MATERIALS AND METHODS: were assessed using various antagonists. RESULTS: -free solution. CONCLUSION: in the treatment of hypertension. This effect may be due in part to the plant's vasorelaxant activity and the presence of compounds such as phenol in plant extracts.

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Publication Details

Journal
Pharmaceutical Biology
Published
2026-04-15
DOI
https://doi.org/10.1080/13880209.2026.2651482
Primary Topic
Heavy Metals in Plants
Type
article
Field-Weighted Citation Impact
0.00

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article

Cardioprotective effect of hydroalcoholic extract stem bark of Xeroderris stuhlmannii on cadmium chloride-induced hypertension and its possible vasorelaxant mechanism on isolated aortic rats

Willifred Dongmo Tékapi Tsopgni, Jacquy Joyce Wanche Kojom, Alain Bertrand Dongmo, Timo D. Stark et al.
Pharmaceutical Biology
Heavy Metals in Plants
article

Cardioprotective effect of hydroalcoholic extract stem bark of Xeroderris stuhlmannii on cadmium chloride-induced hypertension and its possible vasorelaxant mechanism on isolated aortic rats

Willifred Dongmo Tékapi Tsopgni, Jacquy Joyce Wanche Kojom, Alain Bertrand Dongmo, Timo D. Stark, Anatole Guy Blaise Azébazé, Russelle Camelie Nguemnang Tchatchouang
article en

Abstract

BACKGROUND: is a medicinal plant, widely used in Cameroonian folk medicine to treat hypertension. OBJECTIVE: in hypertensive rats and to explore the vasorelaxant mechanisms of its hydroalcoholic extract and to determine the compounds responsible of the activities. MATERIALS AND METHODS: were assessed using various antagonists. RESULTS: -free solution. CONCLUSION: in the treatment of hypertension. This effect may be due in part to the plant's vasorelaxant activity and the presence of compounds such as phenol in plant extracts.

Pharmaceutical BiologyVol. 64(1)
Université de Yaoundé I (CM), University of Douala (CM), Leibniz-Institute for Food Systems Biology at the Technical University of Munich (DE)
Alexander von Humboldt-Stiftung
Openalex Percentile: Top 24%
Heavy Metals in Plants
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