Cardioprotective effect of hydroalcoholic extract stem bark of <i>Xeroderris stuhlmannii</i> on cadmium chloride-induced hypertension and its possible vasorelaxant mechanism on isolated aortic rats
BACKGROUND: is a medicinal plant, widely used in Cameroonian folk medicine to treat hypertension. OBJECTIVE: in hypertensive rats and to explore the vasorelaxant mechanisms of its hydroalcoholic extract and to determine the compounds responsible of the activities. MATERIALS AND METHODS: were assessed using various antagonists. RESULTS: -free solution. CONCLUSION: in the treatment of hypertension. This effect may be due in part to the plant's vasorelaxant activity and the presence of compounds such as phenol in plant extracts.
Authors
- Willifred Dongmo Tékapi Tsopgni (ORCID: https://orcid.org/0000-0002-1644-8171)
- Jacquy Joyce Wanche Kojom (ORCID: https://orcid.org/0000-0002-1569-0193)
- Alain Bertrand Dongmo (ORCID: https://orcid.org/0000-0002-6354-4318)
- Timo D. Stark (ORCID: https://orcid.org/0000-0002-6502-173X)
- Anatole Guy Blaise Azébazé
- Russelle Camelie Nguemnang Tchatchouang
Institutions
- Université de Yaoundé I (CM)
- University of Douala (CM)
- Leibniz-Institute for Food Systems Biology at the Technical University of Munich (DE)
Publication Details
- Journal
- Pharmaceutical Biology
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1080/13880209.2026.2651482
- Primary Topic
- Heavy Metals in Plants
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Alexander von Humboldt-Stiftung