Associations of Circadian Rhythms with Cognitive Performance in Patients with Amnestic Mild Cognitive Impairment (aMCI)

Although sleep-wake timing and melatonin phase did not differ between groups nor predict cognitive performance, higher daily rhythm stability was linked to better non-verbal memory and executive functioning. In contrast, high RA may relate to poorer verbal memory in aMCI, suggesting that elevated RA may not reflect true circadian robustness required for optimal cognition.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-15
DOI
https://doi.org/10.3390/jcm15083023
Primary Topic
Circadian rhythm and melatonin
Type
article
Field-Weighted Citation Impact
0.00

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article

Associations of Circadian Rhythms with Cognitive Performance in Patients with Amnestic Mild Cognitive Impairment (aMCI)

Seong Jae Kim, Jung Hie Lee, Jae‐Won Jang, In Bum Suh
Journal of Clinical Medicine
Circadian rhythm and melatonin
article

Associations of Circadian Rhythms with Cognitive Performance in Patients with Amnestic Mild Cognitive Impairment (aMCI)

Seong Jae Kim, Jung Hie Lee, Jae‐Won Jang, In Bum Suh
article en

Abstract

Although sleep-wake timing and melatonin phase did not differ between groups nor predict cognitive performance, higher daily rhythm stability was linked to better non-verbal memory and executive functioning. In contrast, high RA may relate to poorer verbal memory in aMCI, suggesting that elevated RA may not reflect true circadian robustness required for optimal cognition.

Journal of Clinical MedicineVol. 15(8)
Chosun University (KR), Kangwon National University (KR), Korean Red Cross (KR), Seoul National University Hospital (KR), Suwon Research Institute (KR)
National Research Foundation of Korea
No poverty
Openalex Percentile: Top 19%
Circadian rhythm and melatonin
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