Evaluation of the reliability of large language models for ASA-PS classification in cardiovascular surgery: a pilot study

Large language models (LLMs) have shown promising performance for ASA Physical Status (ASA-PS) classification, but prior work suggests reduced agreement in high-risk patients. We evaluated LLM reliability for ASA-PS classification in cardiovascular surgery. Thirty-two anonymized cases were rated by two residents, two board-certified cardiovascular anesthesiologists, and four LLM modes (ChatGPT: GPT-5.2 Instant and GPT-5.2 Thinking; Gemini: Gemini 3 Fast and Gemini 3 High Thinking); all LLM assessments were zero-shot. Overall agreement across evaluators was moderate (intraclass correlation coefficient [ICC] 0.49–0.52); agreement between each LLM and specialists was good (ICC 0.61–0.65). Exact-match to a five-specialist consensus was 42.2% for residents versus 59.4–75.0% for LLMs; classifications outside the range of ratings assigned by individual specialists were rare (0–3.1%). In cardiovascular surgery, contemporary LLMs showed good concordance with cardiovascular anesthesiologists and exceeded resident agreement with expert consensus, supporting prospective multicenter validation as adjuncts for ASA-PS assessment and training.

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Publication Details

Journal
JA Clinical Reports
Published
2026-04-15
DOI
https://doi.org/10.1186/s40981-026-00858-4
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00

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article

Evaluation of the reliability of large language models for ASA-PS classification in cardiovascular surgery: a pilot study

Shogo Tsujikawa, Koichi Suehiro, Takashi Juri, Hideki Hino et al.
JA Clinical Reports
Artificial Intelligence in Healthcare and Education
article

Evaluation of the reliability of large language models for ASA-PS classification in cardiovascular surgery: a pilot study

Shogo Tsujikawa, Koichi Suehiro, Takashi Juri, Hideki Hino, Yusuke Funai, Takashi Mori, Keisuke Iwabu
article en

Abstract

Large language models (LLMs) have shown promising performance for ASA Physical Status (ASA-PS) classification, but prior work suggests reduced agreement in high-risk patients. We evaluated LLM reliability for ASA-PS classification in cardiovascular surgery. Thirty-two anonymized cases were rated by two residents, two board-certified cardiovascular anesthesiologists, and four LLM modes (ChatGPT: GPT-5.2 Instant and GPT-5.2 Thinking; Gemini: Gemini 3 Fast and Gemini 3 High Thinking); all LLM assessments were zero-shot. Overall agreement across evaluators was moderate (intraclass correlation coefficient [ICC] 0.49–0.52); agreement between each LLM and specialists was good (ICC 0.61–0.65). Exact-match to a five-specialist consensus was 42.2% for residents versus 59.4–75.0% for LLMs; classifications outside the range of ratings assigned by individual specialists were rare (0–3.1%). In cardiovascular surgery, contemporary LLMs showed good concordance with cardiovascular anesthesiologists and exceeded resident agreement with expert consensus, supporting prospective multicenter validation as adjuncts for ASA-PS assessment and training.

JA Clinical Reports
Osaka City University (JP), Osaka City University Hospital (JP)
Edwards Lifesciences, Otsuka Pharmaceutical
Quality Education
Openalex Percentile: Top 8%
Artificial Intelligence in Healthcare and Education
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