Evaluation of the reliability of large language models for ASA-PS classification in cardiovascular surgery: a pilot study
Large language models (LLMs) have shown promising performance for ASA Physical Status (ASA-PS) classification, but prior work suggests reduced agreement in high-risk patients. We evaluated LLM reliability for ASA-PS classification in cardiovascular surgery. Thirty-two anonymized cases were rated by two residents, two board-certified cardiovascular anesthesiologists, and four LLM modes (ChatGPT: GPT-5.2 Instant and GPT-5.2 Thinking; Gemini: Gemini 3 Fast and Gemini 3 High Thinking); all LLM assessments were zero-shot. Overall agreement across evaluators was moderate (intraclass correlation coefficient [ICC] 0.49–0.52); agreement between each LLM and specialists was good (ICC 0.61–0.65). Exact-match to a five-specialist consensus was 42.2% for residents versus 59.4–75.0% for LLMs; classifications outside the range of ratings assigned by individual specialists were rare (0–3.1%). In cardiovascular surgery, contemporary LLMs showed good concordance with cardiovascular anesthesiologists and exceeded resident agreement with expert consensus, supporting prospective multicenter validation as adjuncts for ASA-PS assessment and training.
Authors
- Shogo Tsujikawa (ORCID: https://orcid.org/0000-0003-3268-5203)
- Koichi Suehiro (ORCID: https://orcid.org/0000-0002-2156-6092)
- Takashi Juri (ORCID: https://orcid.org/0000-0003-3510-7388)
- Hideki Hino (ORCID: https://orcid.org/0000-0002-1079-2692)
- Yusuke Funai (ORCID: https://orcid.org/0000-0002-8757-3738)
- Takashi Mori
- Keisuke Iwabu
Institutions
- Osaka City University (JP)
- Osaka City University Hospital (JP)
Publication Details
- Journal
- JA Clinical Reports
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1186/s40981-026-00858-4
- Primary Topic
- Artificial Intelligence in Healthcare and Education
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Edwards Lifesciences
- Otsuka Pharmaceutical