Meiotic gene expression of STAG3 and DMC1 in blood: A novel non-invasive biomarker approach for diminished ovarian reserve: A case-control study

Background: are meiosis-specific genes essential for chromosomal integrity and homologous recombination. While their downregulation in granulosa cells of DOR women has been reported, expression in peripheral blood remains unexplored. Objective: expression as potential non-invasive biomarkers in DOR. Materials and Methods: Ct method. Results: dysregulation in DOR pathogenesis. Conclusion: as a promising non-invasive biomarker for early detection of DOR and contributing to a better understanding of its molecular basis in reproductive medicine.

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Publication Details

Journal
International Journal of Reproductive BioMedicine (IJRM)
Published
2026-04-15
DOI
https://doi.org/10.18502/ijrm.v24i2.21050
Primary Topic
Reproductive Biology and Fertility
Type
article
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article

Meiotic gene expression of STAG3 and DMC1 in blood: A novel non-invasive biomarker approach for diminished ovarian reserve: A case-control study

M Eslami Abrand Abadi, Fateme Montazeri, Nasrin Ghasemi, Farzaneh Iravani et al.
International Journal of Reproductive BioMedicine (IJRM)
Reproductive Biology and Fertility
article

Meiotic gene expression of STAG3 and DMC1 in blood: A novel non-invasive biomarker approach for diminished ovarian reserve: A case-control study

M Eslami Abrand Abadi, Fateme Montazeri, Nasrin Ghasemi, Farzaneh Iravani, Seyed Mehdi Kalantar, Khosro Namjoo
article en

Abstract

Background: are meiosis-specific genes essential for chromosomal integrity and homologous recombination. While their downregulation in granulosa cells of DOR women has been reported, expression in peripheral blood remains unexplored. Objective: expression as potential non-invasive biomarkers in DOR. Materials and Methods: Ct method. Results: dysregulation in DOR pathogenesis. Conclusion: as a promising non-invasive biomarker for early detection of DOR and contributing to a better understanding of its molecular basis in reproductive medicine.

International Journal of Reproductive BioMedicine (IJRM)Vol. 24(2)
Shahid Sadoughi University of Medical Sciences and Health Services (IR)
Gender equality
Openalex Percentile: Top 20%
Reproductive Biology and Fertility
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