Meiotic gene expression of STAG3 and DMC1 in blood: A novel non-invasive biomarker approach for diminished ovarian reserve: A case-control study
Background: are meiosis-specific genes essential for chromosomal integrity and homologous recombination. While their downregulation in granulosa cells of DOR women has been reported, expression in peripheral blood remains unexplored. Objective: expression as potential non-invasive biomarkers in DOR. Materials and Methods: Ct method. Results: dysregulation in DOR pathogenesis. Conclusion: as a promising non-invasive biomarker for early detection of DOR and contributing to a better understanding of its molecular basis in reproductive medicine.
Authors
- M Eslami Abrand Abadi
- Fateme Montazeri (ORCID: https://orcid.org/0000-0002-7739-5982)
- Nasrin Ghasemi (ORCID: https://orcid.org/0000-0002-1103-6004)
- Farzaneh Iravani (ORCID: https://orcid.org/0000-0002-3855-2869)
- Seyed Mehdi Kalantar
- Khosro Namjoo
Institutions
- Shahid Sadoughi University of Medical Sciences and Health Services (IR)
Publication Details
- Journal
- International Journal of Reproductive BioMedicine (IJRM)
- Published
- 2026-04-15
- DOI
- https://doi.org/10.18502/ijrm.v24i2.21050
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 0.00