Amyloidogenic pituitary prolactinoma

ABSTRACT: A 29-year-old man presented with a headache and right-sided visual deficit. His neurological examination was normal except for bilateral optic atrophy. CEMRI revealed a uniformly contrast-enhancing multilobulated lesion at the sellar and suprasellar region. Prolactin levels were high, with the value of 12,800 ng/mL (normal range 3-5 ng/mL) according to hormonal analysis. The pituitary adenoma was removed transsphenoidally from the patient. Histological examination revealed an adenoma with spheroid amyloid deposits adjacent to prolactin-staining adenoma cells. The patient recovered from the surgery without any complications.