Molecular insights into the dual activation of PomZ, a ParA/MinD P-loop ATPase, by the two ATPase-activating proteins PomX and PomY

may involve two distinct, non-overlapping binding sites at the dimer interface of ATP-bound PomZ. Altogether, these results provide insights into the molecular mechanism of activation by two AAPs of a ParA/MinD ATPase.

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Publication Details

Journal
mBio
Published
2026-04-15
DOI
https://doi.org/10.1128/mbio.00425-26
Primary Topic
Bacterial Genetics and Biotechnology
Type
article
Field-Weighted Citation Impact
0.00

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article

Molecular insights into the dual activation of PomZ, a ParA/MinD P-loop ATPase, by the two ATPase-activating proteins PomX and PomY

Lotte Søgaard‐Andersen, Philipp Klos, Andrea Harms
mBio
Bacterial Genetics and Biotechnology
article

Molecular insights into the dual activation of PomZ, a ParA/MinD P-loop ATPase, by the two ATPase-activating proteins PomX and PomY

Lotte Søgaard‐Andersen, Philipp Klos, Andrea Harms
article en

Abstract

may involve two distinct, non-overlapping binding sites at the dimer interface of ATP-bound PomZ. Altogether, these results provide insights into the molecular mechanism of activation by two AAPs of a ParA/MinD ATPase.

mBio
Max Planck Institute for Terrestrial Microbiology (DE)
Max-Planck-Gesellschaft
Openalex Percentile: Top 14%
Bacterial Genetics and Biotechnology
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