Mouse TAPBPR shows functional similarity to human TAPBPR in shaping the MHC-I immunopeptidome
. Together, our findings suggest that mouse TAPBPR plays an important role in shaping the MHC-I immunopeptidome by functioning as a peptide editor, similar to its human counterpart.
Authors
- Aure Aflalo (ORCID: https://orcid.org/0000-0002-7158-6868)
- Arwen F. Altenburg (ORCID: https://orcid.org/0000-0002-5361-4909)
- Andreas Neerincx (ORCID: https://orcid.org/0000-0002-6902-5383)
- Marcel Wacker (ORCID: https://orcid.org/0000-0002-8185-140X)
- Alison McDowall (ORCID: https://orcid.org/0000-0003-2018-1462)
- Juliana Bernardi Aggio (ORCID: https://orcid.org/0000-0002-7512-3211)
- Louise H. Boyle (ORCID: https://orcid.org/0000-0002-3105-6555)
- Ida Hafstrand (ORCID: https://orcid.org/0000-0002-1012-9532)
- J Bauer
- Reem Satti
- Juliane S. Walz (ORCID: https://orcid.org/0000-0001-6404-7391)
- K Skjodt
- Mikkel‐Ole Skjoedt
- Alice Abreu Torres
- William Guo
- Jack Welland
Institutions
- University of Copenhagen (DK)
- University of Southern Denmark (DK)
- University of Cambridge (GB)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- German Center for Infection Research (DE)
- Institute of Immunology (HR)
- University of Tübingen (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-04-15
- DOI
- https://doi.org/10.3389/fimmu.2026.1756668
- Primary Topic
- vaccines and immunoinformatics approaches
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Carl-Zeiss-Stiftung
- Wellcome Trust
- Cancer Research UK
- Deutsche Forschungsgemeinschaft
- Else Kröner-Fresenius-Stiftung
- Deutsche Krebshilfe
- Deutschen Konsortium für Translationale Krebsforschung