Giant Pseudoangiomatous Stromal Hyperplasia Presenting as Bilateral Macromastia in an 11-Year-Old Female Patient: Emphasis on Pediatric Presentation and Literature Review
≈ 1072). Pediatric lesions showed significantly higher rates of bilaterality (50% vs <1%), diffuse/macromastic growth (58% vs <1%), larger mean size (18.3 cm vs 4-5 cm), and greater need for mastectomy (42% vs 1.5%). Our observations from clinical presentations in the literature and our from patient demonstrate that pediatric PASH has the potential to present as rapid, massive bilateral breast enlargement, suggesting that pediatric PASH is not merely a smaller form of the adult disease but a distinct clinical entity requiring age-appropriate management.
Authors
- Shubha Dave (ORCID: https://orcid.org/0000-0003-1975-6230)
- Mai Thy Tran (ORCID: https://orcid.org/0009-0000-3408-1054)
- Sydney Rashid
Institutions
- West Virginia University (US)
Publication Details
- Journal
- International Journal of Surgical Pathology
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1177/10668969261439154
- Primary Topic
- Breast Lesions and Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00