“Efficacy of mind–body interventions on cognitive function in middle-aged and older adults via hormonal modulation: A narrative review”

Aging may bring about mild cognitive changes; however, substantial cognitive decline is typically a sign of pathological aging, not a normal biological marker. Aging is promoted by stress, lack of sleep, and consumption of processed and preservative foods. According to more recent research, age-related variations in cognitive function may also be linked to the hormonal imbalance, despite other factors. Mind-body medicine is gaining popularity day by day because of its cost-effectiveness and easy approachability, with no side effects. Mind-body practices have a great effect on cognition by improving the brain structure, like the right dorsal medial frontal lobe, left dorsal frontal lobe, right prefrontal cortex, right sensorimotor cortex, right inferior frontal lobe, the amygdala, and the hippocampus. Mind-body practices also improve the HPA axis, Sympathetic nervous system, and HPA axis play an important role in hormone homeostasis. Ageing increases the concentration of Catabolic hormones, such as cortisol, thyroxine, and triiodothyronine, which impact mood, brain function, and cognition in addition to promoting bodily activity and metabolic processes during acute stress.DHEAs have anti-glucocorticoid activity and protect the structure of neurons, counteracting the neurotoxic effects of cortisol. Sex hormones improve cognition. In this manuscript, we are trying to establish a hypothesis that Mind-Body Medicine improves cognitive function by balancing cognitive hormones.