Recurrent Acute Tonsillitis: Re-evaluating Surgical Indications Through Long-Term Outcome Assessment
OBJECTIVES: To investigate whether current tonsillectomy (TE) guidelines for adults with recurrent acute tonsillitis (RT) are too restrictive, potentially excluding patients who would benefit from surgery, and to explore predictive factors of improved postoperative Throat-Related Quality of Life (TR-QoL). METHODS: In this prospective cohort study, patients undergoing TE were stratified into 3 groups based on increasingly stringent criteria: G1 (not meeting the Danish National Guidelines (DNG) or the Scottish Intercollegiate Guidelines Network [SIGN]/Paradise criteria), G2 (meeting only DNG), and G3 (meeting both DNG and SIGN/Paradise criteria). The effects of TE were assessed using the Tonsillectomy Outcome Inventory 14 (TOI-14) and the Glasgow Benefit Inventory (GBI). TOI-14 scores, GBI scores, patient satisfaction and postoperative sore throat episodes were evaluated after 12, 24 and 36 months. Predictive factors of improved TR-QOL were identified using multiple linear regression. RESULTS: = 0.723). CONCLUSIONS: TE provided sustained benefits and significantly improved TR-QoL across a broad range of RT patients, including those who did not meet current guideline criteria, suggesting that guidelines may be too restrictive. The preoperative TOI-14 score was the strongest predictor of TR-QoL improvement. Integrating such a patient-centered tool to select patients for TE may enhance RT patient management.
Authors
- Tejs Ehlers Klug (ORCID: https://orcid.org/0000-0001-5053-8034)
- Hannah Inez Houborg (ORCID: https://orcid.org/0000-0003-2658-246X)
Institutions
- Aarhus University (DK)
- Aarhus University Hospital (DK)
Publication Details
- Journal
- Annals of Otology Rhinology & Laryngology
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1177/00034894261437481
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Aarhus Universitet
- Aase og Ejnar Danielsens Fond
- Lundbeckfonden
- Torben og Alice Frimodts Fond