Recurrent Acute Tonsillitis: Re-evaluating Surgical Indications Through Long-Term Outcome Assessment

OBJECTIVES: To investigate whether current tonsillectomy (TE) guidelines for adults with recurrent acute tonsillitis (RT) are too restrictive, potentially excluding patients who would benefit from surgery, and to explore predictive factors of improved postoperative Throat-Related Quality of Life (TR-QoL). METHODS: In this prospective cohort study, patients undergoing TE were stratified into 3 groups based on increasingly stringent criteria: G1 (not meeting the Danish National Guidelines (DNG) or the Scottish Intercollegiate Guidelines Network [SIGN]/Paradise criteria), G2 (meeting only DNG), and G3 (meeting both DNG and SIGN/Paradise criteria). The effects of TE were assessed using the Tonsillectomy Outcome Inventory 14 (TOI-14) and the Glasgow Benefit Inventory (GBI). TOI-14 scores, GBI scores, patient satisfaction and postoperative sore throat episodes were evaluated after 12, 24 and 36 months. Predictive factors of improved TR-QOL were identified using multiple linear regression. RESULTS: = 0.723). CONCLUSIONS: TE provided sustained benefits and significantly improved TR-QoL across a broad range of RT patients, including those who did not meet current guideline criteria, suggesting that guidelines may be too restrictive. The preoperative TOI-14 score was the strongest predictor of TR-QoL improvement. Integrating such a patient-centered tool to select patients for TE may enhance RT patient management.

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Publication Details

Journal
Annals of Otology Rhinology & Laryngology
Published
2026-04-15
DOI
https://doi.org/10.1177/00034894261437481
Primary Topic
Obstructive Sleep Apnea Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Recurrent Acute Tonsillitis: Re-evaluating Surgical Indications Through Long-Term Outcome Assessment

Tejs Ehlers Klug, Hannah Inez Houborg
Annals of Otology Rhinology & Laryngology
Obstructive Sleep Apnea Research
article

Recurrent Acute Tonsillitis: Re-evaluating Surgical Indications Through Long-Term Outcome Assessment

Tejs Ehlers Klug, Hannah Inez Houborg
article en

Abstract

OBJECTIVES: To investigate whether current tonsillectomy (TE) guidelines for adults with recurrent acute tonsillitis (RT) are too restrictive, potentially excluding patients who would benefit from surgery, and to explore predictive factors of improved postoperative Throat-Related Quality of Life (TR-QoL). METHODS: In this prospective cohort study, patients undergoing TE were stratified into 3 groups based on increasingly stringent criteria: G1 (not meeting the Danish National Guidelines (DNG) or the Scottish Intercollegiate Guidelines Network [SIGN]/Paradise criteria), G2 (meeting only DNG), and G3 (meeting both DNG and SIGN/Paradise criteria). The effects of TE were assessed using the Tonsillectomy Outcome Inventory 14 (TOI-14) and the Glasgow Benefit Inventory (GBI). TOI-14 scores, GBI scores, patient satisfaction and postoperative sore throat episodes were evaluated after 12, 24 and 36 months. Predictive factors of improved TR-QOL were identified using multiple linear regression. RESULTS: = 0.723). CONCLUSIONS: TE provided sustained benefits and significantly improved TR-QoL across a broad range of RT patients, including those who did not meet current guideline criteria, suggesting that guidelines may be too restrictive. The preoperative TOI-14 score was the strongest predictor of TR-QoL improvement. Integrating such a patient-centered tool to select patients for TE may enhance RT patient management.

Annals of Otology Rhinology & Laryngology
Aarhus University (DK), Aarhus University Hospital (DK)
Aarhus Universitet, Aase og Ejnar Danielsens Fond, Lundbeckfonden, Torben og Alice Frimodts Fond
Openalex Percentile: Top 15%
Obstructive Sleep Apnea Research
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Recurrent Acute Tonsillitis: Re-evaluating Surgical Indications Through Long-Term Outcome Assessment — Tejs Ehlers Klug, Hannah Inez Houborg · Annals of Otology Rhinology & Laryngology (2026) | TGRS Research Map | TGRS