Multiplex FET biosensor with vapor-deposited molecularly imprinted nanotubes for cancer biomarkers
(CA125) and 0.05-10 pM (HE4). Selectivity factors of 11.3 and 23.7 were obtained for the CA125 sensor and the HE4 sensor, respectively, indicating high specificity of the imprinted sensors for their respective target biomarkers. By combining vapor-deposited MIP nanotubes with a compact FET architecture, our work offers a promising route toward early, point-of-care diagnosis through the simultaneous quantification of multiple cancer biomarkers.
Authors
- Faruk Can (ORCID: https://orcid.org/0000-0002-9651-123X)
- Gözde Özaydın İnce (ORCID: https://orcid.org/0000-0003-3255-4940)
- Selma Takmakli
- Ali Ebil (ORCID: https://orcid.org/0009-0005-3481-3477)
- Elaheh Yousefimiab (ORCID: https://orcid.org/0009-0007-1582-5442)
- Ufuk Ulas Tokat
Institutions
- Sabancı Üniversitesi (TR)
- Interface (United States) (US)
Publication Details
- Journal
- Nanotechnology
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1088/1361-6528/ae5fa2
- Primary Topic
- Analytical chemistry methods development
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu