Sex-dependent role of inflammatory biomarkers in Alzheimer's disease-related cognitive performance
= 0.032), suggesting a role for SHBG in sex-dependent inflammatory pathways related to cognitive performance.ConclusionsPeripheral inflammatory biomarkers, particularly IL-21, showed sex-specific links to plasma P-tau181 and non-memory impairment in ADNI, supporting sex-stratified analyses.
Authors
- B Zhang
- Shiyue Wang (ORCID: https://orcid.org/0000-0002-0355-3132)
- Xicheng Yu
- Suwen Huang (ORCID: https://orcid.org/0009-0003-3711-1505)
- Ruting Wei
- Dehao Yang
- Jinrong Zhu
- Jiaxuan Chen
- Bingxin Teng
- Guangyong Chen
- Yiyun Weng (ORCID: https://orcid.org/0000-0002-1407-4276)
- Bohao Li
- Hejia Cai
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Ruian People's Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1177/13872877261440932
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China