Dexmedetomidine Use and Reduced In-hospital Mortality in ICU Patients with Delirium: A Retrospective Study Based on Two Observational Cohorts

< 0.0001). Propensity score analyses confirmed these findings. Furthermore, mortality at 90 days, 180 days, and 1 year was also significantly reduced in the dexmedetomidine group.ConclusionsDexmedetomidine administration during ICU stay correlates with a reduced mortality risk in critically ill patients suffering from delirium.

Authors

Sai Zhou
刘惠萍
WENMING SONG
Huan Chang (ORCID: https://orcid.org/0009-0005-8908-5761)
Gong Chen (ORCID: https://orcid.org/0009-0002-6232-2331)
Lizhi Fu

Institutions

Central South University (CN)
Changsha Medical University (CN)
The First People's Hospital of Changde (CN)
Third Xiangya Hospital (CN)

Publication Details

Journal: Journal of Intensive Care Medicine
Published: 2026-04-15
DOI: https://doi.org/10.1177/08850666261440805
Primary Topic: Intensive Care Unit Cognitive Disorders
Type: article
Field-Weighted Citation Impact: 0.00

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article

Dexmedetomidine Use and Reduced In-hospital Mortality in ICU Patients with Delirium: A Retrospective Study Based on Two Observational Cohorts

Sai Zhou, 刘惠萍, WENMING SONG, Huan Chang et al.

Apr 15, 2026

Journal of Intensive Care Medicine

Intensive Care Unit Cognitive Disorders

article

Dexmedetomidine Use and Reduced In-hospital Mortality in ICU Patients with Delirium: A Retrospective Study Based on Two Observational Cohorts

Sai Zhou, 刘惠萍, WENMING SONG, Huan Chang, Gong Chen, Lizhi Fu

April 15, 2026article en

Abstract

< 0.0001). Propensity score analyses confirmed these findings. Furthermore, mortality at 90 days, 180 days, and 1 year was also significantly reduced in the dexmedetomidine group.ConclusionsDexmedetomidine administration during ICU stay correlates with a reduced mortality risk in critically ill patients suffering from delirium.

Journal of Intensive Care Medicine

Central South University (CN), Changsha Medical University (CN), The First People's Hospital of Changde (CN), Third Xiangya Hospital (CN)

Good health and well-being

Openalex Percentile: Top 14%

Intensive Care Unit Cognitive Disorders

DOI Source OpenAlex

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