Association of biofilm formation with multidrug resistance in burn wound patients isolates of Pseudomonas aeruginosa in Sana’a City, Yemen
Background: is recognized for its ability to acquire multidrug resistance (MDR) and form biofilms that enhance virulence and antimicrobial tolerance. Objective: isolates from burn wound infections in Sana'a City, Yemen. Methods: ≤ 0.05 considered significant. Results: > 0.05). Conclusion: remains the leading cause of burn wound infections in Sana'a City, Yemen, exhibiting alarmingly high levels of carbapenem and cephalosporin resistance. Although biofilm formation was common, no significant association was found between biofilm production and multidrug resistance. The high prevalence of PDR strains underscores the urgent need for antimicrobial stewardship, routine susceptibility testing, and infection control measures in burn centers.
Authors
- Abdulrahman Y. Al-Haifi (ORCID: https://orcid.org/0000-0001-7242-7052)
- Yaser Mohammed Al‐Worafi (ORCID: https://orcid.org/0000-0002-5752-2913)
- Ali Salman Al-Shami (ORCID: https://orcid.org/0000-0002-7135-5111)
- Hammood Mohammed Naji Saad
- Ahmed Yahia Al-Jaufy
- Ansam M. Al-Barq
- Hude Z. Al-Shami
- Abdulhakim M. Al-Saban
- Zaid Abdo Thawaba
- Abdullah Ahmed Al-Dhabali
- Eshtiaq A. Al-Yosffi
- Abdullah H. Maad
- Ahlam Ali Maher
Institutions
- Sana'a University (YE)
- Alta View Hospital (US)
- College of Medical Sciences (NP)
- Thamar University (YE)
- Al-Saeeda University (YE)
- Al-Ameen College of Pharmacy (IN)
- Oklahoma State University Center for Health Sciences (US)
- Lebanese International University (LB)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-04-15
- DOI
- https://doi.org/10.3389/fmed.2026.1762684
- Primary Topic
- Bacterial biofilms and quorum sensing
- Type
- article
- Field-Weighted Citation Impact
- 0.00