Case Report: Neurological brucellosis with behavioral abnormalities: a case of Brucella encephalitis with mild cognitive impairment

has emerged as the dominant strain. Meanwhile, strains associated with cattle and pigs have seen a decline in prevalence. Although neurological brucellosis is relatively rare among brucellosis cases, it presents a considerable challenge due to its non-specific symptoms and diverse clinical manifestations, which often lead to misdiagnosis or delayed recognition. The most commonly reported symptoms of neurological brucellosis include headaches, along with visual disturbances, hearing impairment, confusion, sleep disorders, seizures, agitation, depression, and signs of peripheral nerve involvement. In instances of encephalitis, alterations in consciousness and focal neurological deficits are frequently observed. Furthermore, it is important to note that certain patients may display psychiatric or behavioral changes. In such instances, obtaining a comprehensive epidemiological history and conducting thorough laboratory tests are essential for an accurate diagnosis.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-04-15
DOI
https://doi.org/10.3389/fmed.2026.1809313
Primary Topic
Brucella: diagnosis, epidemiology, treatment
Type
article
Field-Weighted Citation Impact
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article

Case Report: Neurological brucellosis with behavioral abnormalities: a case of Brucella encephalitis with mild cognitive impairment

Xueyun Wang, Yinlan Su, Wenjing Deng
Frontiers in Medicine
Brucella: diagnosis, epidemiology, treatment
article

Case Report: Neurological brucellosis with behavioral abnormalities: a case of Brucella encephalitis with mild cognitive impairment

Xueyun Wang, Yinlan Su, Wenjing Deng
article en

Abstract

has emerged as the dominant strain. Meanwhile, strains associated with cattle and pigs have seen a decline in prevalence. Although neurological brucellosis is relatively rare among brucellosis cases, it presents a considerable challenge due to its non-specific symptoms and diverse clinical manifestations, which often lead to misdiagnosis or delayed recognition. The most commonly reported symptoms of neurological brucellosis include headaches, along with visual disturbances, hearing impairment, confusion, sleep disorders, seizures, agitation, depression, and signs of peripheral nerve involvement. In instances of encephalitis, alterations in consciousness and focal neurological deficits are frequently observed. Furthermore, it is important to note that certain patients may display psychiatric or behavioral changes. In such instances, obtaining a comprehensive epidemiological history and conducting thorough laboratory tests are essential for an accurate diagnosis.

Frontiers in MedicineVol. 13
Fourth People’s Hospital of Jinan (CN), Affiliated Hospital of Jining Medical University (CN)
Good health and well-being
Openalex Percentile: Top 26%
Brucella: diagnosis, epidemiology, treatment
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