Identification of risk factors of cystic periventricular leukomalacia in preterm infants

Introduction: The neonatal period in very preterm born infants is characterized by high vulnerability of the developing brain. Diffuse or cystic white matter injury-cystic periventricular leukomalacia (cPVL)-is one of the most serious complications leading to brain injury in preterm infants, associated with an increased risk of neurological impairments such as cerebral palsy. Methods: ), calculated from routinely measured parameters using a mathematical model. Results: . The obtained results may be useful for future risk assessment of cPVL at an early stage.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2026-04-15
DOI
https://doi.org/10.3389/fped.2026.1758972
Primary Topic
Neonatal and fetal brain pathology
Type
article
Field-Weighted Citation Impact
0.00

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article

Identification of risk factors of cystic periventricular leukomalacia in preterm infants

Christian Brickmann, Renée Lampe, Eva Lück, Irina Sidorenko et al.
Frontiers in Pediatrics
Neonatal and fetal brain pathology
article

Identification of risk factors of cystic periventricular leukomalacia in preterm infants

Christian Brickmann, Renée Lampe, Eva Lück, Irina Sidorenko, Ursula Felderhoff-Müser, Andrey Kovtanyuk, Marcus Krüger
article en

Abstract

Introduction: The neonatal period in very preterm born infants is characterized by high vulnerability of the developing brain. Diffuse or cystic white matter injury-cystic periventricular leukomalacia (cPVL)-is one of the most serious complications leading to brain injury in preterm infants, associated with an increased risk of neurological impairments such as cerebral palsy. Methods: ), calculated from routinely measured parameters using a mathematical model. Results: . The obtained results may be useful for future risk assessment of cPVL at an early stage.

Frontiers in PediatricsVol. 14
München Klinik Schwabing (DE), Schön Klinik München Harlaching (DE), Essen University Hospital (DE), München Klinik Harlaching (DE), University of Duisburg-Essen (DE), Technical University of Munich (DE)
Technische Universität München, Stiftung Würth, Klaus Tschira Stiftung
Openalex Percentile: Top 22%
Neonatal and fetal brain pathology
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