Associations Between Alcohol Dehydrogenase Mutations and Cleft Lip/Palate: A Scoping Review
in a family with CL ± P cases.ConclusionsCurrent evidence, though limited, suggests that certain maternal and fetal ADH polymorphisms may influence risk of fetal CL ± P. Existing data have been primarily limited to demographically homogenous cohorts, and ancestry was not analyzed in concert with ADH polymorphisms. The interaction of ancestry, ADH mutations, and CL ± P remains an important, open question.
Authors
- Theodore Hyman (ORCID: https://orcid.org/0009-0002-2294-2878)
- Natasha Shur (ORCID: https://orcid.org/0000-0003-1336-747X)
- Gary F. Rogers (ORCID: https://orcid.org/0000-0002-9568-0365)
- Perry Bradford
- Esperanza Mantilla‐Rivas (ORCID: https://orcid.org/0000-0001-9821-1241)
- Monica Manrique
- Athena Zhang (ORCID: https://orcid.org/0009-0008-6229-1698)
- Albert K. Oh (ORCID: https://orcid.org/0000-0002-3555-9184)
- Sofia A. Finestone (ORCID: https://orcid.org/0000-0003-4422-9635)
- Liara Ortiz Ocasio
Institutions
- National Hospital (IN)
Publication Details
- Journal
- The Cleft Palate-Craniofacial Journal
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1177/10556656261438751
- Primary Topic
- Prenatal Substance Exposure Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00