Capillaroscopic patterns are associated with interstitial lung disease, skin fibrosis, anti-Th/To antibodies and quality of life in systemic sclerosis: a prospective cross-sectional study

Background: Capillaroscopic patterns in systemic sclerosis (SSc) are routinely assessed by nailfold videocapillaroscopy (NVC), yet their broader clinical relevance remains incompletely defined. Methods: -values were adjusted using the false discovery rate (FDR). Results: = 0.019) most likely reflecting greater disease severity rather than a treatment effect. Conclusion: Our study demonstrates significant associations between NVC severity and selected clinical, serological, therapeutic, and patient-reported domains in SSc.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-04-15
DOI
https://doi.org/10.3389/fmed.2026.1808581
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
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article

Capillaroscopic patterns are associated with interstitial lung disease, skin fibrosis, anti-Th/To antibodies and quality of life in systemic sclerosis: a prospective cross-sectional study

Jakub Trefler, Hubert Czaplicki, Katarzyna Życińska, Anna Pasierb et al.
Frontiers in Medicine
Systemic Sclerosis and Related Diseases
article

Capillaroscopic patterns are associated with interstitial lung disease, skin fibrosis, anti-Th/To antibodies and quality of life in systemic sclerosis: a prospective cross-sectional study

Jakub Trefler, Hubert Czaplicki, Katarzyna Życińska, Anna Pasierb, Lidia Lech
article en

Abstract

Background: Capillaroscopic patterns in systemic sclerosis (SSc) are routinely assessed by nailfold videocapillaroscopy (NVC), yet their broader clinical relevance remains incompletely defined. Methods: -values were adjusted using the false discovery rate (FDR). Results: = 0.019) most likely reflecting greater disease severity rather than a treatment effect. Conclusion: Our study demonstrates significant associations between NVC severity and selected clinical, serological, therapeutic, and patient-reported domains in SSc.

Frontiers in MedicineVol. 13
Medical University of Warsaw (PL), Ministry of Interior (IT)
Openalex Percentile: Top 25%
Systemic Sclerosis and Related Diseases
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