Metformin Treatment Shows Beneficial Effects on RTT-Associated Phenotypical Deficits in Mecp2 T158M Male Mice
: Our findings provide evidence for potential therapeutic effects of metformin for MeCP2-associated neurological disorders.
Authors
- Ashraf Kadar Shahib (ORCID: https://orcid.org/0009-0009-8641-7969)
- Carl O. Olson
- Chris-Tiann Roberts (ORCID: https://orcid.org/0009-0002-8872-5542)
- Mojgan Rastegar (ORCID: https://orcid.org/0000-0003-3619-6116)
- Ghanan Bin Akhtar
- Abbas Rezaeian Mehrabadi
- Khatereh Saei Arezoumand
- Jessica S. Jarmasz (ORCID: https://orcid.org/0000-0002-3487-9610)
Institutions
- University of Manitoba (CA)
Publication Details
- Journal
- Pharmaceuticals
- Published
- 2026-04-15
- DOI
- https://doi.org/10.3390/ph19040621
- Primary Topic
- Genetics and Neurodevelopmental Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Children's Hospital Research Institute of Manitoba
- Canadian Institutes of Health Research