Electrospun PCL/PLGA–biogenic hydroxyapatite nanofibers with bioactive additives: physicochemical characterization and <i>in vitro</i> mineralization
m depending on additive composition. SBF immersion demonstrated apatite layer formation, indicating good mineralization potential. Swelling ratio analysis showed additive-dependent hydration behavior, with amoxicillin (143%) and propolis (129%) significantly increasing swelling, while EW produced moderate swelling (79%) compared to the base scaffold (63%). Overall, the hybrid scaffolds demonstrated synergistic physicochemical stability and bioactivity, supporting their potential use as functional biomaterial platforms.
Authors
- Diana Julaidy Patty (ORCID: https://orcid.org/0000-0002-7981-7819)
- Yusril Yusuf (ORCID: https://orcid.org/0000-0001-9104-9333)
- Ika Dewi Ana
Institutions
- Universitas Gadjah Mada (ID)
- University of Pattimura (ID)
- Universitas Respati Yogyakarta (ID)
Publication Details
- Journal
- Biomedical Physics & Engineering Express
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1088/2057-1976/ae5f9f
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00