HERBAL OPHTHALMIC DRUG DELIVERY: A COMPREHENSIVE REVIEW

The purpose of the review is the Dry eye disease is a multifactorial disorder of the tear film and ocular surface that cause discomfort visual disturbance and potential damage to the eye. Ophthalmic treatment like hyaluronic acid based eye drop, hydroxypropylmetylcellulose, and nano emulsion provide temporary relief because of the poor drug bioavailability and ocular barriers. To overcome these there are herbal drug is used like Aloe Vera. Aloe Vera has many active constituents which include vitamin, enzyme, anthraquinone, and polysaccharide which give the anti- inflammatory, antioxidant, antimicrobial, and wound healing, which is helpful in the restore tear film, reduce inflammation and promote the corneal health in DES. Hence the aloe Vera based ophthalmic drug delivery gives safe, biocompatible, and conventional synthetic treatment for dry eye disease.