PHARMACEUTICAL STANDARDIZATION OF GUDUCHI SATVA AND GUDUCHI GHANA KALPANA PREPARED FROM TINOSPORA CORDIFOLIA

Pharmaceutical standardization of Ayurvedic medicines is necessary to ensure quality, safety and efficacy of drugs. An immense valuable and powerful medicine in the form of metals, minerals and plants are found in the nature. But, most of the drugs as such are not absorbable into the biological systems until & unless they have certain modifications. The specialized techniques to make these drugs absorbable therapeutically or clinically viable is called pharmaceutical process. Even a small dose of drug may give powerful action, by carrying out these pharmaceutical processes. In Bhaishajaya kalpana Satva words denotes herbal preparations Eg. Nimbuk satva, Guduchi satva etc. Description of satva was firstly found in Yogaratanakar in Rajakshama Chikatsa in context of Guduchyadi modak, same quotations were mentioned in A.F.I. In A.F.I. standard procedure of preparation was also mentioned. Important Therapeutic Use of Guduchi satva: Kshaya (Pthisis), Raktapitta Bleeding disorder), Padadaha (Burning sensation of feet). Some properties of Guduchi satva mentioned in Yogaratanakar in Praibhasa Prakarana these are as follows; Strong antipyretic, If taken in proper age, then acts as Rasayana, Useful in Jawara Daha, Prameha, Aruchi, Trusha, Swasa, Pandu, Arsha, Hikka, Leucorrhoea in females. The colour of final product was pure white. Ghana is concentrated form of dosage forms, which is mostly used for internal administration. In our classics, Rasakriya is also considered as Phanita, Avaleha and Ghana, because their method of preparation is almost the same with minor variations. Ghana Kalpana: Kwatha and others (Swarasa, Kalka etc.) when further processed with heat become thicker and thicker in consistency (viscous- to - semisolid- to solid) that is termed as Rasakriya. Thus, the herbal liquid material with the help of heat is processed till it solidifies, which ultimately can be made in to powder/tablet form, which is called Ghana. According to references Ghana is more solid than Avaleha. Fine powdered Ghana was dark brown in colour.