Maternal Exposure to Bisphenol A Bis(diphenyl Phosphate) Induces Offspring Colitis through Disrupting the Gut Microbiome-Metabolite Axis

α), which were subsequently confirmed by in vitro experiments. These findings demonstrate a transgenerational mechanism whereby prenatal BDP exposure induces offspring colonic inflammation via the gut microbiome-metabolite axis, informing maternal-infant intervention strategies.

Authors

C Li
Yi Luo (ORCID: https://orcid.org/0000-0003-0007-0394)
G. Zhang
Jie Yang (ORCID: https://orcid.org/0000-0003-4801-7162)
Zicheng Jin
Chengze Tan
Xin Wang
Xueqiong Zhou

Institutions

Guangdong Provincial Center for Disease Control and Prevention (CN)
Southern Medical University (CN)

Publication Details

Journal: Environmental Science & Technology
Published: 2026-04-15
DOI: https://doi.org/10.1021/acs.est.5c11474
Primary Topic: Effects and risks of endocrine disrupting chemicals
Type: article
Field-Weighted Citation Impact: 0.00

Funders

National Natural Science Foundation of China
Guangzhou Municipal Science and Technology Project

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article

Maternal Exposure to Bisphenol A Bis(diphenyl Phosphate) Induces Offspring Colitis through Disrupting the Gut Microbiome-Metabolite Axis

C Li, Yi Luo, G. Zhang, Jie Yang et al.

Apr 15, 2026

Environmental Science & Technology

Effects and risks of endocrine disrupting chemicals

article

Maternal Exposure to Bisphenol A Bis(diphenyl Phosphate) Induces Offspring Colitis through Disrupting the Gut Microbiome-Metabolite Axis

C Li, Yi Luo, G. Zhang, Jie Yang, Zicheng Jin, Chengze Tan, Xin Wang, Xueqiong Zhou

April 15, 2026article en

Abstract

α), which were subsequently confirmed by in vitro experiments. These findings demonstrate a transgenerational mechanism whereby prenatal BDP exposure induces offspring colonic inflammation via the gut microbiome-metabolite axis, informing maternal-infant intervention strategies.

Environmental Science & TechnologyVol. 60(16)

Guangdong Provincial Center for Disease Control and Prevention (CN), Southern Medical University (CN)

National Natural Science Foundation of China, Guangzhou Municipal Science and Technology Project

Good health and well-being

Openalex Percentile: Top 16%

Effects and risks of endocrine disrupting chemicals

DOI Source OpenAlex

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