Assessing the Validity of the Fellow Eye as an Internal Control in Early-Phase Clinical Trials for Myopic Chorioretinal Atrophy

This study quantitatively supports the feasibility and methodological validity of inter-ocular comparison designs for early-phase clinical trials in myopic CRA.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-15
DOI
https://doi.org/10.3390/jcm15082997
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessing the Validity of the Fellow Eye as an Internal Control in Early-Phase Clinical Trials for Myopic Chorioretinal Atrophy

Kohei Uemura, Shuntaro Ogura, Soichiro Kuwayama, Takahiro Hojo et al.
Journal of Clinical Medicine
Retinal Diseases and Treatments
article

Assessing the Validity of the Fellow Eye as an Internal Control in Early-Phase Clinical Trials for Myopic Chorioretinal Atrophy

Kohei Uemura, Shuntaro Ogura, Soichiro Kuwayama, Takahiro Hojo, N Nagano, Yoshio Hirano, Masayo Kimura, Tsutomu Yasukawa, Yukinori Sakaeda, Eisaku Kanemori, Hiroshi Morita, Takaaki Yuguchi
article en

Abstract

This study quantitatively supports the feasibility and methodological validity of inter-ocular comparison designs for early-phase clinical trials in myopic CRA.

Journal of Clinical MedicineVol. 15(8)
Tokyo University of Information Sciences (JP), Nagoya City University (JP), The University of Tokyo (JP)
Sustainable cities and communities
Openalex Percentile: Top 15%
Retinal Diseases and Treatments
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Assessing the Validity of the Fellow Eye as an Internal Control in Early-Phase Clinical Trials for Myopic Chorioretinal Atrophy — Kohei Uemura, Shuntaro Ogura, et al. · Journal of Clinical Medicine (2026) | TGRS Research Map | TGRS