Uterine Papillary Serous Carcinoma (UPSC): A Rare Case Report

Uterine papillary serous carcinoma (UPSC) accounts for 5-10% endometrial cancers, although they account for majority of endometrial cancer mortality. This case report discusses a 58-year-old female menopausal for fifteen years presented with vaginal discharge for two months, post-menopausal bleeding for 20 days, and lower abdominal pain after 20 days. Bloating, vomiting, constipation, increased urine frequency, and abnormal uterine bleeding were eventually diagnosed as Uterine Papillary Serous Carcinoma (UPSC).The case emphasizes the limitations of early identification, the significance of histological confirmation, and the therapeutic choices for controlling this aggressive tumor.

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Journal
Annals of King Edward Medical University
Published
2026-03-31
DOI
https://doi.org/10.21649/akemu.v32i1.5993
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
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article

Uterine Papillary Serous Carcinoma (UPSC): A Rare Case Report

Saba Shahid, Eman Khan, Safwan Saleh, Maryam Mushtaq
Annals of King Edward Medical University
Endometrial and Cervical Cancer Treatments
article

Uterine Papillary Serous Carcinoma (UPSC): A Rare Case Report

Saba Shahid, Eman Khan, Safwan Saleh, Maryam Mushtaq
article en

Abstract

Uterine papillary serous carcinoma (UPSC) accounts for 5-10% endometrial cancers, although they account for majority of endometrial cancer mortality. This case report discusses a 58-year-old female menopausal for fifteen years presented with vaginal discharge for two months, post-menopausal bleeding for 20 days, and lower abdominal pain after 20 days. Bloating, vomiting, constipation, increased urine frequency, and abnormal uterine bleeding were eventually diagnosed as Uterine Papillary Serous Carcinoma (UPSC).The case emphasizes the limitations of early identification, the significance of histological confirmation, and the therapeutic choices for controlling this aggressive tumor.

Annals of King Edward Medical UniversityVol. 32(1)
Rawalpindi Medical University (PK), CMH Lahore Medical College and Institute of Dentistry (PK), Shalamar Hospital (PK)
Good health and well-being
Openalex Percentile: Top 8%
Endometrial and Cervical Cancer Treatments
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Uterine Papillary Serous Carcinoma (UPSC): A Rare Case Report — Saba Shahid, Eman Khan, et al. · Annals of King Edward Medical University (2026) | TGRS Research Map | TGRS