Comparative analysis of DNA methyltransferase 3 alpha and miR-29b expression in eutopic and ectopic endometrial tissues from endometriosis patients compared to healthy controls: A case-control study
Background: ) alpha, an important DNA methyltransferase, and miR-29b, a known suppressor of methyltransferase expression, may play a related role in this disease. Objective: expression in eutopic and ectopic endometrial tissues from women with endometriosis compared to endometrial tissues from healthy controls. Materials and Methods: were analyzed by real-time polymerase chain reaction. Glyceraldehyde 3-phosphate dehydrogenase was used as a normalization control. Results: . Conclusion: in endometriotic tissues suggests their involvement in the pathogenesis of the disease. These molecules could serve as potential diagnostic biomarkers or therapeutic targets in endometriosis.
Authors
- Emad Babakhanzadeh (ORCID: https://orcid.org/0000-0003-3392-7999)
- Maryam Shirmohamadi (ORCID: https://orcid.org/0000-0003-0585-5414)
- Javad Fazeli
- Ali Dadbinpour
- Mahta Mazaheri-Naeini
- Milad Taatnezhad
Institutions
- Shahid Sadoughi University of Medical Sciences and Health Services (IR)
Publication Details
- Journal
- International Journal of Reproductive BioMedicine (IJRM)
- Published
- 2026-04-15
- DOI
- https://doi.org/10.18502/ijrm.v24i2.21051
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00