Effect of the cardiac long non-coding RNA Charme depletion on the maturation and paracrine signaling of resident cardiac fibroblasts
mice. These findings pave the way to deeper investigations on the intercellular signaling occurring in the heart upon Charme ablation to identify how microenvironment homeostasis contributes to cardiomyocyte maturation and is potentially involved in cardiac diseases.
Authors
- Carmine Nicoletti (ORCID: https://orcid.org/0000-0001-5896-2040)
- Antonella Bordin (ORCID: https://orcid.org/0000-0002-9236-5327)
- Valeria Taliani (ORCID: https://orcid.org/0000-0001-6449-735X)
- Francesca Pagano (ORCID: https://orcid.org/0000-0003-1956-5864)
- Giulia Buonaiuto (ORCID: https://orcid.org/0000-0002-4099-2433)
- Xhulio Dhori
- Erica Floris (ORCID: https://orcid.org/0000-0002-8012-4681)
- Vittorio Picchio (ORCID: https://orcid.org/0000-0003-1591-5118)
- Monica Ballarino (ORCID: https://orcid.org/0000-0002-8595-7105)
- Isotta Chimenti (ORCID: https://orcid.org/0000-0002-0865-8814)
- Giacomo Frati (ORCID: https://orcid.org/0000-0001-5584-6060)
- Francesco Nutile
- Alessandro Palma
Institutions
- National Center for Supercomputing Applications (BG)
- Istituto Neurologico Mediterraneo (IT)
- Maria Cecilia Hospital (IT)
- Institute of Cell Biology and Neurobiology (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Cell Death and Disease
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1038/s41419-026-08636-x
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Sapienza Università di Roma