Ablation-First Balloon-Assisted Acetabuloplasty for Painful Acetabular Metastases: Clinical Outcomes and Mechanical Rationale

PURPOSE: To evaluate the safety, technical feasibility, and clinical outcomes of a strict two-step protocol-CT/fluoroscopic-guided thermal ablation followed by Balloon-Assisted Acetabuloplasty (BAA)-for the treatment of painful acetabular metastases, utilized as an immediate mechanical stabilization bridge prior to radiotherapy. MATERIALS AND METHODS: A retrospective study was conducted on 16 consecutive patients treated for severe mechanical pain (VAS ≥ 6) and impaired mobility due to osteolytic acetabular metastases. The physiological rationale mandated a strict procedural sequence: (1) preliminary thermal devitalization using radiofrequency or microwave ablation to reduce tumor pressure and vascularity, followed subsequently by (2) balloon-assisted cavity compaction and polymethylmethacrylate (PMMA) cement injection. Clinical outcomes included VAS for pain and the Functional Mobility Scale (FMS) assessed before treatment and up to 6 months post-procedure. RESULTS: < 0.001), allowing independent ambulation in 87.5% of patients. CONCLUSION: The strict "ablation-first" BAA strategy is safe and highly effective. It abolishes load-bearing pain and restores biomechanical stability immediately, allowing previously immobilized patients to rapidly regain independent ambulation and seamlessly transition to necessary consolidative radiotherapy.

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Publication Details

Journal
Current Oncology
Published
2026-04-15
DOI
https://doi.org/10.3390/curroncol33040217
Primary Topic
Management of metastatic bone disease
Type
article
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article

Ablation-First Balloon-Assisted Acetabuloplasty for Painful Acetabular Metastases: Clinical Outcomes and Mechanical Rationale

José María Maiques Llácer, Claudio Pusceddu, Salvatore Marsico, Eliodoro Faiella et al.
Current Oncology
Management of metastatic bone disease
article

Ablation-First Balloon-Assisted Acetabuloplasty for Painful Acetabular Metastases: Clinical Outcomes and Mechanical Rationale

José María Maiques Llácer, Claudio Pusceddu, Salvatore Marsico, Eliodoro Faiella, Albert Solano López, Jesús Ares-Vidal, Igor Radalov, Pierluigi Rinaldi
article en

Abstract

PURPOSE: To evaluate the safety, technical feasibility, and clinical outcomes of a strict two-step protocol-CT/fluoroscopic-guided thermal ablation followed by Balloon-Assisted Acetabuloplasty (BAA)-for the treatment of painful acetabular metastases, utilized as an immediate mechanical stabilization bridge prior to radiotherapy. MATERIALS AND METHODS: A retrospective study was conducted on 16 consecutive patients treated for severe mechanical pain (VAS ≥ 6) and impaired mobility due to osteolytic acetabular metastases. The physiological rationale mandated a strict procedural sequence: (1) preliminary thermal devitalization using radiofrequency or microwave ablation to reduce tumor pressure and vascularity, followed subsequently by (2) balloon-assisted cavity compaction and polymethylmethacrylate (PMMA) cement injection. Clinical outcomes included VAS for pain and the Functional Mobility Scale (FMS) assessed before treatment and up to 6 months post-procedure. RESULTS: < 0.001), allowing independent ambulation in 87.5% of patients. CONCLUSION: The strict "ablation-first" BAA strategy is safe and highly effective. It abolishes load-bearing pain and restores biomechanical stability immediately, allowing previously immobilized patients to rapidly regain independent ambulation and seamlessly transition to necessary consolidative radiotherapy.

Current OncologyVol. 33(4)
Cambia (AU), Hospital Del Mar (ES), Campus Bio Medico University Hospital (IT)
Good health and well-being
Openalex Percentile: Top 26%
Management of metastatic bone disease
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