[177Lu]Lu-PSMA extravasation: from quantitative imaging to clinical guidelines

[177Lu]Lu-PSMA extravasation undergoes rapid clearance under conservative management, with absorbed doses below deterministic thresholds and unaffected systemic biodistribution. Conservative interventions-massage, warming, and arm elevation are therefore justified. Automated quantitative dosimetry enables same-day dose estimation, providing an objective basis for timely clinical decision-making and paving the way toward standardized management protocols.