A review on ethnobotanical uses, geographical distribution, phytochemistry, quality control and pharmacology of <i>Anemone</i> L. plants distributed in the northeastern region of China

Regel in the Chinese Pharmacopoeia. Pharmacological studies reveal that these compounds exhibit significant anti-cancer, anti-inflammatory, antioxidant, and analgesic activities. Notably, raddeanoside R3 induces apoptosis in osteosarcoma, glioblastoma, gastric cancer, and breast cancer cells. Despite these advances, further research is needed to elucidate the anti-rheumatic properties of these species and to establish comprehensive quality control standards for all six species.