A novel shaping technique for advanced platelet rich fibrin
This article presents a novel technique for shaping advanced platelet-rich fibrin (A-PRF) to precisely fill uniform defects while preserving its biological integrity and regenerative capacity, with relevance to Oral & Maxillofacial Surgery. We present two clinical cases illustrating the use of soft tissue punch biopsy tools to accurately shape A-PRF plugs. In each case, appropriately sized punches were used to conform A-PRF to the dimensions of the defect—screw holes following bimaxillary osteotomy, and a sinus tract resulting from post-radiotherapy wound breakdown. The technique enabled precise, easy handling of A-PRF while maintaining its natural structure and biological properties, avoiding the loss of growth factors typically associated with compression. This technique offers a straightforward, predictable method for shaping A-PRF to precisely fit uniform cylindrical defects while preserving the natural fibrin architecture. It has the potential to simplify operative handling and optimise defect adaptation, facilitating optimal healing.
Authors
- Valmiki Sharma (ORCID: https://orcid.org/0000-0003-2259-6792)
- Sarika Shivji
- Tara Gulshan
Institutions
- Luton and Dunstable University Hospital NHS Foundation Trust (GB)
Publication Details
- Journal
- Discover Medicine
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1007/s44337-026-00600-0
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00