Tetrazolylidene-Stabilized Gold(I) Complexes: Synthesis and Evaluation of Anticancer Activity <i>In Vitro</i>
= 63.2-86.7) and potent antiproliferative effects in the low submicromolar range against A2780, outperforming cisplatin and matching the activity of auranofin. Overall, the results presented here demonstrate the potential of gold(I) tetrazolylidene-based complexes for medicinal applications.
Authors
- Fritz E. Kühn (ORCID: https://orcid.org/0000-0002-4156-780X)
- C Schmidt
- Alexander Pöthig (ORCID: https://orcid.org/0000-0003-4663-3949)
- Leon F. Richter (ORCID: https://orcid.org/0000-0003-2948-9156)
- Simon Stifel
- Angela Casini (ORCID: https://orcid.org/0000-0003-1599-9542)
Institutions
- Technical University of Munich (DE)
Publication Details
- Journal
- Inorganic Chemistry
- Published
- 2026-04-15
- DOI
- https://doi.org/10.1021/acs.inorgchem.6c00049
- Primary Topic
- Synthesis of Tetrazole Derivatives
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Graduate School, Technische Universität München