Evaluating corneal topographic patterns in keratoconic eyes and their association with keratoconus changes over time

AIM: To evaluate various corneal topographic patterns in keratoconus (KCN) and their association with disease progression. METHODS: A retrospective cohort study was conducted on 636 eyes of 335 KCN patients (396 males, 240 females) with a mean age of 30.95±7.95y. Participants underwent two ocular examinations, including corneal tomography using the Pentacam-HR. Topographic patterns were classified based on axial curvature, and KCN progression was defined as a change of ≥1.00 D in maximum keratometry (Kmax). Accordingly, evaluated eyes were categorized into progressive, regressive, and stable groups. RESULTS: <0.05). CONCLUSION: Corneal topographic patterns in KCN exhibit distinct characteristics and progression rates. Understanding these patterns can aid in predicting disease progression and tailoring treatment strategies.